Live Better
SMA and the new miracle drug Spinraza
Spinal muscular atrophy, or SMA, is a genetic disease that attacks nerve cells in the spinal cord. These nerve cells, known as motor neurons, communicate with the voluntary muscles in the body, such as those in the arms and legs. As more neurons are lost, muscles start to weaken and breathing, crawling, swallowing, and walking can become more difficult. It also can be difficult for those with SMA to control movements in their heads and necks. Though SMA runs in families, parents can exhibit no symptoms but still carry the gene. There are many types of SMA, and, according to the National Institute of Neurological Disorders and Stroke, the type of SMA is determined by the age of onset and the severity of symptoms. SMA Type I is evident at birth or within the first few months of a child being born. Symptoms may include difficulty swallowing, feeble movements of the arms and legs, loose limbs and trunk, impaired breathing, and a weak sucking reflex. SMA Type II is evident between the ages of six and 18 months, and the legs are typically more impaired than the arms. An early indicator may be a baby who is not crawling or walking. SMA Type III may be evident when a child reaches his or her toddler years, but sometimes does not appear until adolescence. When a child has SMA Type III, he or she may have trembling fingers and may experience difficulty getting up from a sitting position. Children with SMA Type II or Type III are at an increased risk of respiratory infections.
What causes SMA?
According to the Muscular Dystrophy Association, chromosome 5 SMA, the most common form of SMA, is caused by a deficiency of SMN, a motor neuron protein. This protein is necessary for normal motor neuron function, and a deficiency of SMN is caused by mutations on chromosome 5 in the SMN1 gene. Mutations in other genes may also cause SMA, and such cases are referred to as non-chromosome 5 SMA.
What are the symptoms of SMA?
There are various types of SMA, and the symptoms can vary depending on the type of SMA a person has. The following are some of the symptoms associated with the various types of SMA.
- Type 1: Type 1 is the most severe type of SMA. When a child is type 1, he or she may have difficulty supporting his or her head and sitting without help. Difficulty swallowing and weakness in the arms and legs may also occur. The muscles that control breathing also can be compromised when a child has type 1 SMA, and breathing problems can affect a child’s life expectancy.
- Type 2: Type 2 SMA typically affects the legs more than the arms. Type 2 SMA affects children between six and 18 months of age, and such kids may be able to sit, stand or walk with help.
- Type 3: The mildest form of SMA, type 3 may be referred to as juvenile SMA. Children with type 3 can often stand or walk without help, but they may have difficulty climbing stairs, getting up from a chair or running.
- Type 4: Type 4 SMA begins in adulthood, and men and women may experience muscle weakness, twitching or breathing problems. Physical therapy can help men and women better manage their symptoms, which typically only affect the upper arms and legs.
Recently the FDA approved an amazing new drug Spinraza to treat symptoms of SMA and prolong these life of individuals taking Spinraza. With a few injections, patients with SMA may be able to gain muscle strength and live longer by a year or more. It cost $125,000 an injection, and in the first two months one takes 4 injections in the spine. That’s half a million dollars for the first four shots. Subsequent costs for this possibly lifelong therapy are expected to be about $375,000 annually, with about three injections required each year. While this may seem extremely expensive the drug was developed to save lives, along with some resources available to help individuals requiring the drug. With coverage being more readily available to those effected the most, starting with SMA type I. Remember if you are trying to obtain Spinraza use every resource available at your disposal and educate yourself on the drug, available resources, and your healthcare. Don’t be afraid to ask questions and challenge your neurologist who would prescribe Spinraza along with your insurance representative, and if you have to, seek out a social worker for assistance. Be your own advocate. Take into account this drug has been developed and approved in a significantly short amount of time. Spinraza is for a relatively low percentage of the population, lots of money and resources were put into the development of this drug. For more information and resources go to SMAnewstoday.com. Remember to connect yourself with other individuals with SMA to share resources and connect with others who are going through the same thing you may be experiencing with SMA.
Parents can also learn more about SMA by visiting the Muscular Dystrophy Association online at www.mda.org & www.curesma.org
(Feature Impact) Travelers are more likely to trust a travel advisor over AI when the trip becomes complicated, expensive or likely to change. According to new research from ALG Vacations, a leading vacation package provider, 77% of AI users say they are likely to still rely on a human to make final travel decisions when using AI to plan.
The pattern is strongest among younger travelers. Millennials and Gen Z are using travel advisors at the highest rates of any generation, even as they also report higher trust in AI travel recommendations. Younger travelers are using AI and travel advisors for different parts of the same trip.
Are Millennials and Gen Z still using travel advisors?
Yes. Younger travelers are using both AI and travel advisors. In fact, among AI users, the youngest generations use travel advisors most:
- 51% of Millennials have used a travel advisor when booking a vacation
- 51% of Gen Z say the same
- 44% of Baby Boomers report advisor use
- 43% of Gen X report advisor use
The same generations leading on advisor use are also the most trusting of AI travel recommendations. Among AI users, 31% of both Millennials and Gen Z say they completely trust travel recommendations generated by AI, compared with 12% of Baby Boomers. They are using both.
When should you use a travel advisor instead of AI?
Consider using a travel advisor over AI when the stakes are high. AI users turn to travel advisors most often in these scenarios:
- 36% when something goes wrong, such as a canceled flight or a double-booked hotel
- 31% for complex or multi-destination trips
- 27% for group or family travel
- 27% for luxury or high-cost trips
When forced to choose between AI and a travel advisor for final vacation decisions, 44% of AI users pick a travel advisor and 37% pick AI. Among Baby Boomers, the gap widens sharply, with 59% picking a travel advisor and 15% picking AI.
What does a travel advisor bring that AI cannot?
Travel advisors bring human judgment, planning experience and direct support when a trip becomes more complicated. Among AI users, 82% say having access to a human for support when booking a vacation is extremely or very important.
That support matters when travelers are comparing options, booking a higher-cost trip, coordinating multiple people or adjusting plans after a disruption. AI can organize information quickly, but travelers still cite practical concerns about relying on it entirely.
The specific value travel advisors provide includes:
- Relationships with the people who run resorts, hotels and tour operators
- Access to deals and amenities not always available to the public
- Firsthand experience and industry knowledge
- Real-time support when plans change
- Judgment and personalization for complex trip planning
The top concerns AI users have about relying entirely on AI include important details being missed (42%), privacy or security concerns (42%) and having no support if something goes wrong (39%).
Is AI going to replace travel advisors?
No. The data shows AI and travel advisors, still commonly known as travel agents, serving complementary roles rather than competing ones.
AI is used for the research and inspiration stages of travel planning. Travel advisors are used for the booking, more complex decisions and moments when travelers want a person involved.
AI is now part of how people plan trips. Travel advisors are too. The travelers most comfortable using AI are also the ones turning to advisors most often.
To learn more about ALG Vacations and connect with a travel advisor, visit alg.www.vaxvacationaccess.com.
Methodology
ALG Vacations commissioned Atomik Research to conduct an online survey of 1,000 U.S. adults who currently use AI tools. The margin of error is plus or minus 3 percentage points at a 95 percent confidence level. Fieldwork was conducted between April 24 and April 28, 2026.
Atomik Research, part of 4media group, is a creative market research agency.
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(Feature Impact)For most households, buying a new vehicle is one of the largest financial decisions they’ll make. The purchase price is only the beginning, however. Fuel, maintenance, depreciation and insurance all contribute to the total cost of ownership, making affordability a consideration that extends well beyond the showroom.
To help consumers make more informed purchasing decisions, Mercury Insurance recently released its annual rankings of the most affordable new 2026 model year vehicles to insure, identifying the top-performing SUV, truck, sedan and electric or hybrid vehicles in four of today’s most popular categories.
“Consumers naturally compare purchase price, fuel economy, safety ratings and technology features before buying a vehicle,” said Chong Gao, director of research and development for Mercury Insurance. “Insurance is one of the few ownership costs drivers can estimate before making a purchase. Factoring it into the decision gives consumers a more complete picture of what that vehicle is likely to cost over the years they own it.”
While every driver’s premium is unique, this year’s rankings also revealed a broader trend: Practical, mainstream vehicles continue to offer some of the strongest long-term insurance value.
“Vehicles designed for everyday drivers often strike the best balance between safety, repairability and replacement costs,” Gao said. “That’s reflected in this year’s rankings, where familiar models from manufacturers like Hyundai, Chevrolet, Honda, Kia and Volkswagen rose to the top. It reinforces the idea that choosing a practical vehicle can pay dividends well beyond the purchase price.”
A Cost You Can Plan For
Unlike unexpected repairs or fluctuating fuel prices, insurance is a predictable ownership expense consumers can research before purchasing a vehicle.
Comparing insurance costs alongside purchase price, fuel economy, maintenance expenses and expected repair costs can help shoppers better understand the long-term financial commitment of vehicle ownership.
Factors Influencing Insurance Costs
Insurance costs are influenced by many factors, but repair complexity, parts availability, vehicle safety systems and historical claims experience all contribute to how a vehicle is insured. While advanced safety technology can help reduce accidents, vehicles that are easier and less expensive to repair can also help improve long-term affordability. Among the considerations insurers evaluate are:
- Repair and replacement costs
- Historical claims experience
- Vehicle safety features and crash performance
- Theft frequency
- Availability and cost of replacement parts
- Vehicle performance characteristics
The Most Affordable Vehicles to Insure
This year’s rankings show practical, mainstream vehicles continue to offer some of the strongest insurance value. The top spot in both the SUV and electric and hybrid categories was claimed by Hyundai while Chevrolet led the truck category and Volkswagen topped the sedan rankings. Rounding out Mercury’s rankings were several familiar nameplates recognized for balancing insurance affordability with everyday value.
SUVs:
- Hyundai Santa Fe
- Chevrolet Blazer
- Honda Pilot
- Kia Sportage
- Honda Passport
Trucks:
- Chevrolet Colorado LT
- Chevrolet Silverado C3500
- Ford Maverick and Ranger
- Hyundai Santa Cruz SE
- Toyota Tundra CrewMax
Sedans and Coupes:
- Volkswagen Golf R
- Acura Integra
- Honda Prelude
- Kia K4
- Mazda3
Electric and Hybrids:
- Hyundai Santa Fe Hybrid
- Chevrolet Blazer EV
- Kia Sportage Hybrid
- Ford Escape Hybrid
- Honda CR-V Hybrid
“The smartest vehicle purchase isn’t always the one with the lowest sticker price,” Gao said. “It’s the one that delivers the best overall value over time. Comparing insurance before buying gives consumers another tool to make a more informed decision.”
Visit MercuryInsurance.com to see the full rankings and request a quote to get a more complete understanding of long-term ownership costs.
Photo courtesy of Hyundai America (Hyundai Santa Fe)
Photo courtesy of Shutterstock (couple using laptop)
(Feature Impact) Summertime means sunshine, longer days, family vacations and social events everywhere you look – but summer can slip away if you feel too tired and distracted to make the most of your experiences.
According to a survey conducted by Atomik Research on behalf of Botanic Tonics, many adults ages 21 and older struggle to feel fully present in summer activities. Nearly half of respondents said having enough energy and a clear mind would help them get more enjoyment out of the summer moments that matter most.
With that in mind, here are five simple daily habits to support your energy and focus throughout the rest of the summer season.
Improve Your Sleep Quality
It might sound obvious, but getting better sleep should be a top priority for anyone trying to harness more physical and mental energy throughout the day. Keep your bedroom cool, dark and quiet; avoid consuming caffeine too close to bedtime; and wind down with a relaxing routine like reading or yoga.
Get Regular Exercise
Even though a workout consumes energy in the short term, it pays you back with dividends. Just 30 minutes of movement a day – including favorite summer activities like swimming or playing games in the yard – can improve your mood. Physical movement also helps reduce stress, which was a reported obstacle for 33% of survey respondents who wished they could be more present with friends and family during the summer months.
Stay Hydrated
When the weather is hot, it becomes more important to stay on top of your hydration. Even mild dehydration can negatively impact your energy and focus. When you’re out of the house, bring a reusable water bottle and set reminders to drink regularly, especially during and after outdoor activities.
Limit Device Usage
When you’re feeling sluggish, it can be tempting to collapse on the couch or in bed to scroll on your phone or watch TV. There’s nothing wrong with screen time in moderation, but digital fatigue is real and it can drain your energy and disrupt your sleep. Plus, 49% of surveyed adults said social-media-driven FOMO (“fear of missing out”) made it harder for them to enjoy their summer experiences in the moment.
Try Botanical Energy Offerings
When energy levels start to dip, it’s easy to reach for a cup of coffee, a sugary energy drink or soda. Products made with thoughtfully sourced botanical ingredients offer a different approach. For example, Botanic Tonics’ “feel free” kava-centric supplements are designed to deliver chilled energy: a unique combination of energy, focus and elevated mood.
For smooth, sustained energy without caffeine jitters or sugar crashes, try KavaMaté, crafted with noble kava root and yerba maté. For those looking to elevate their mood and enhance focus, feel free Classic is thoughtfully crafted with noble kava root and natural whole leaf kratom – never synthetic ingredients, alcohol or concentrates.
Learn more about these products, responsible consumption and where to purchase at BotanicTonics.com.
Photo courtesy of Shutterstock
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