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Making Alzheimer’s just a memory

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An in-depth look at Alzheimer’s and work to find a cure

(Family Features) Although the COVID-19 pandemic turned the world upside down, the rapid development of multiple vaccines has spurred hope that treatments – or even potential cures – may be found for other devastating conditions. One such candidate is Alzheimer’s Disease.

Understanding Alzheimer’s

The Alzheimer’s Association defines the disease as a type of dementia that affects memory, thinking and behavior. While some degree of memory loss is common with age, Alzheimer’s symptoms are significant enough to affect a person’s daily life and typically only grow worse over time.

Early signs of Alzheimer’s include trouble remembering new information, solving problems or completing familiar tasks. As the disease progresses, disorientation, confusion, significant memory loss and changes in mood or behavior may become apparent. Physical symptoms may include difficulty speaking, swallowing or walking.

Impact of Alzheimer’s

Among people aged 65 and older, 1 in 9 (11.3%) has been diagnosed with Alzheimer’s Disease, meaning more than 6 million Americans live with it. Worldwide, the World Health Organization estimates there are nearly 50 million people living with dementia, and Alzheimer’s likely accounts for 60-70% of those. By 2050, this number could rise as high as 13 million. Less commonly noted are the numbers of early-onset (under 65 years old) Alzheimer’s patients within those figures. Up to 9% of global Alzheimer’s cases are believed to be early onset, according to the World Health Organization.

According to a Harvard School of Public Health survey, Alzheimer’s is second only to cancer among America’s most feared diseases. However, data from the Alzheimer’s Association shows Alzheimer’s is the sixth-leading cause of death in the United States, a rate higher than breast cancer and prostate cancer combined.

Beyond the personal impact for those battling the disease and their loved ones, Alzheimer’s Disease also takes a significant economic toll. The Alzheimer’s Association predicts that in 2021, Alzheimer’s and other dementias will cost the nation $355 billion. By 2050, these costs could exceed $1 trillion if no permanent treatment or cure for Alzheimer’s is found. At the same time, more than 11 million Americans provide unpaid care for people with Alzheimer’s and other dementias, an estimated 15.3 billion hours of care, valued at nearly $257 billion.

Milton Todd Ault III, founder of Alzamend Neuro

Treatment Options

While there hasn’t been enough significant progress in discovering a treatment or cure in the more than 100 years since Alzheimer’s was first identified in 1906, early diagnosis and treatment may improve the quality of life for patients. The disease affects each patient differently, so therapies vary widely depending on how far it has progressed and which symptoms are most prevalent. Some therapeutic approaches can address symptoms like sleep disruption and behavior while medication may be beneficial for treating other symptoms.

Founded in 2016 by Milton “Todd” Ault III, Alzamend Neuro, a preclinical-stage biopharmaceutical company, has been actively seeking a cure for Alzheimer’s and concentrates on researching and funding novel products for the treatment of neurodegenerative diseases and psychiatric disorders. With two products currently in development, the company aims to bring these potential therapies to market at a reasonable cost as quickly as possible.

Ault’s stepfather is currently battling Alzheimer’s, his mother-in-law died from the disease and he has three other family members suffering through it.

“Even though work has been done to find a cure for Alzheimer’s, to me it hasn’t been a full-court press,” said Ault, whose many personal encounters with Alzheimer’s have further fueled his passion to find a cure. “While there are no profound treatments today for Alzheimer’s disease, we believe we can change that.”

Practical Ways to Fast-Track a Cure

Some basic changes in the approach to disease research could accelerate progress for diseases like Alzheimer’s, said Milton “Todd” Ault III, founder of Alzamend Neuro.
Ault believes recent advancements in vaccines and medical technology, combined with these five approaches, can help advance the search for a cure for Alzheimer’s disease and other dementias.

Encourage public-private partnerships

The collaboration of government agencies and private industries was integral to the COVID-19 vaccine development. The cross-industry partnerships enabled a vaccine to get to market in less than one year despite detractors. Ault believes this model can be replicated for other diseases and conditions.

Diversify the search

Because of its complexity, a cure for Alzheimer’s will require expertise from a broad range of organizations including health and defense, biopharmaceutical firms, academic experts and those involved in Operation Warp Speed, the federal effort that supported multiple COVID-19 vaccine candidates simultaneously to expedite development.

Share standards and data

Focusing on a shared goal is vital to succeeding. This means looking for ways to share standards and collaborate with colleagues and competitors regardless of proprietary data, patents and other limitations.

Become the catalyst for a cure

When political will and government funding are insufficient or unable to drive change, the private sector can inspire action.

“The progress we are making is a result of the private investment dollars we secured and the way we have applied strategy and tenacity that comes from a successful business record,” Ault said.

Learning from past successes

Aside from the result, there is a great deal to learn from the successful development of past drugs and vaccines. Social awareness and cultural demand are potential ways to stimulate faster production and approvals between public and private entities.

To learn more about treatments and therapies in development visit alzamend.com .

Photo courtesy of Getty Images (Father and daughter)

SOURCE:
Alzamend Neuro

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Everyday Ways to Nurture Your Skin This Summer: 4 simple habits to support healthy skin

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(Family Features) Good skin care doesn’t have to mean intensive routines or expensive moisturizers – it can be as easy as adopting everyday habits that nurture your skin from the inside out. Keeping your skin healthy and glowing begins with protecting it from harmful ultraviolet (UV) rays and eating and drinking healthy foods and beverages.

With an important role in maintaining overall well-being, it’s reassuring to know skin health may be supported with healthy, everyday foods including fresh, juicy grapes. In fact, emerging research suggests consuming grapes may help protect healthy skin even when exposed to UV light, which is known to be damaging. A study published in the journal “Antioxidants,” in which people consumed 2 1/4 cups of grapes every day for two weeks, showed increased resistance to sunburn and reduced markers of UV damage at the cellular level.

This study reinforced previous and similar findings published in the “Journal of the American Academy of Dermatology.” Grapes are also a hydrating food with 82% water content; hydration is essential to healthy skin.

Consider these everyday ways you can protect your skin.

Keep the Sun at Bay
Protecting skin from the sun is crucial. A lifetime of sun exposure can lead to wrinkles, age spots and other health problems, including an increased risk of skin cancer. When you’re out enjoying some sunshine, generously apply sunscreen of at least 30 SPF every 1-2 hours. Covering skin with lightweight, long-sleeve shirts, wide-brimmed hats and other sun-protective clothing can also help block UV rays. Another heat-wave hack: Take to the shade during the hottest parts of the day, usually from 10 a.m. to 4 p.m., to avoid the sun’s rays when they’re at their strongest.

Fill Your Plate with Healthy Foods
Nutritious foods, including fruits and vegetables, can play an important role in achieving an overall balanced diet with adequate hydration. Enjoying the goodness of fresh or frozen Grapes from California can provide extra hydration and a boost of beneficial antioxidants and other polyphenols that help protect the health and function of the body’s cells, including those in the skin.

Stay Hydrated
Drink water throughout the day, and for added flavor, infuse with hydrating fruits like fresh, juicy grapes. For a cool, hydrating snack, try freezing grapes: simply rinse, pat dry, remove from the stems and freeze for 2 hours in a single layer on a sheet pan for flavorful ice cube replacements.

For an easy, refreshing way to add grapes to your menu and stay hydrated on warm days, try these Frozen Grape Lemonade Ice Pops for a sweet, delicious dessert the entire family can enjoy.

Fight Back Against Stress
Stress can negatively impact skin in a variety of ways, including making it more sensitive or reactive. Be mindful of the effects stress can have on your skin and practice stress-relieving techniques like getting enough sleep, exercise and perhaps exploring meditation, deep breathing or yoga.

Visit GrapesFromCalifornia.com for more delicious recipes and information on grapes and health.

Frozen Grape Lemonade Ice Pops

Yield: 8 ice pops

  • 2 cups halved California Grapes
  • 1 1/3 cups lemonade
  1. Fill eight 3-ounce ice pop molds with halved grapes.
  2. Pour in lemonade to just cover fruit. Insert ice pop stick handles.
  3. Freeze at least 3 hours until frozen.


SOURCE:
California Table Grape Commission

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Stay safe, healthy during and after emergencies

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4 tips to prepare for natural disasters that can negatively impact physical and mental health

(Family Features) As you’re making your emergency preparedness checklist, it’s also important to protect your heart and overall health in the wake of a hurricane, tornado or other natural disaster.

The experts at the National Oceanic and Atmospheric Administration predict an above-average Atlantic Ocean hurricane season for the seventh year in a row. Research shows it’s not only physical devastation that impacts the health and safety of people in the path of a natural disaster.

In fact, in a study presented at the American Heart Association’s Epidemiology, Prevention, Lifestyle and Cardiometabolic Health 2021 Scientific Sessions, researchers found there were higher rates of high blood pressure, obesity and pre-diabetes among survivors of Hurricane Maria in Puerto Rico in 2017, as well as increased incidences of heart disease and stroke two years after the storm compared to two years prior to the hurricane.

It’s not only hurricanes that can have a negative impact on cardiovascular health. A study published in the journal “Hypertension found a significant increase in blood pressure levels and the incidence of high blood pressure among people who were forced to evacuate following the Great East Japan Earthquake in 2012.

Gustavo E. Flores, M.D., a member of the American Heart Association’s Emergency Cardiovascular Care committee, said there are several factors that may lead to increased cardiovascular disease and risk after a natural disaster.

“During and after a storm, many people experience extreme stress and trauma, which research shows can lead to an increase in cardiovascular disease risk,” he said. “The impact can be more intense for heart disease and stroke patients. Additionally, in the aftermath of a significant natural disaster, property destruction and evacuations affect many basic support resources. This can make it challenging to see a health care professional for routine check-ups or refill or adjust medications, especially for more vulnerable populations.”

Flores, chairman and chief instructor for Emergency & Critical Care Trainings, LLC, said it’s important for people to be prepared and plan ahead. Consider these quick tips from Flores and the American Heart Association, which is celebrating 100 years of lifesaving service as the world’s leading nonprofit organization focused on heart and brain health for all:

  • Take time to write down any medical conditions, allergies and medications, including doses and the time you take medications, along with your pharmacy name, address and phone number. Keep the information with any other “go-kit” items you have handy for quick evacuation.
  • If you need to evacuate, even temporarily, bring your medications and health information with you in a resealable plastic bag to help keep it dry.
  • If your medication is lost, damaged by water or was left behind when you evacuated, research open pharmacies and seek a refill as quickly as possible. Some states allow pharmacists to make medically necessary exceptions on certain types of prescription refills during an emergency.
  • Use the Patient Preparedness Plan if you have diabetes and use insulin. There you’ll find a checklist of supplies and guidelines to prepare for an emergency.

Another way to prepare for a possible medical emergency is to learn how to perform hands-only cardiopulmonary resuscitation (CPR) and how to use an automated external defibrillator until help arrives. If performed correctly, CPR can double or triple a person’s chance of survival.

Visit Heart.org for the latest on heart health and the Disaster Resources page for a wide range of helpful information.

Photo courtesy of Shutterstock


SOURCE:
American Heart Association

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Nurturing the mental health of young children

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(Family Features) The earliest years of children’s lives lay the foundation for their social and emotional well-being, setting the stage for success in school and beyond. For parents, caregivers and educators, it’s crucial to prioritize and nurture the mental health of children in their care.

Dr. Lauren Loquasto, senior vice president and chief academic officer at The Goddard School, and Dr. Kyle Pruett, clinical professor of child psychiatry at Yale School of Medicine and member of The Goddard School’s Educational Advisory Board, share this insight and guidance to support children’s mental well-being.

Understanding Mental Health in Young Children
Mental health influences how everyone – including young children – thinks, feels and behaves, impacting the ability to cope with stress, build relationships and navigate life.

The development of mental makeup is influenced by both nature (inherited genetic and biological factors) and nurture (environmental factors). Each person is a combination of a unique temperament combined with life experiences, including family, culture and education.

In young children, there is no distinction between mental and physical health. The brain and body are growing and developing rapidly. By 6 months, children can begin to feel overwhelmed by negative experiences. It’s vital to understand that the earliest interactions with children can have lasting social and emotional consequences.

Causes for Concern
When it comes to young children’s mental health, there’s no straight line dividing expected and worrisome behaviors. That line is wiggly and can shift. That said, it’s always concerning when children fall off their developmental tracks.

Infants are expected to partake in “serve and return” activities. They provide signals about how they feel or what they need and caregivers respond to those cues. When those signals stop and the child becomes exceedingly passive, that’s a concern.

Toddler troubles are among the most difficult to diagnose. Many are familiar with the concept of the “terrible twos;” deciphering between developmentally appropriate and worrisome behaviors can be challenging. Signs of concern – especially if they occur constantly – include excessive aggressiveness, a consistent lack of control and screaming instead of talking.

For pre-kindergarteners and kindergarteners, tantrums should be over. They should be interested in making friends and mastering their vocabulary and language. If they aren’t displaying interests or are exhibiting a lack of self-regulation, such as hurting others or animals, seeking help is appropriate.

Seeking Help
If concerns are identified, parents should contact their pediatric care provider. In some cases, they may recommend seeking assistance from a mental health provider, such as a therapist. Selecting the right provider – one with training and experience with working with children – is essential. Lean on your network, including your pediatric care provider, friends and family, to identify the best option.

Supporting Early Social and Emotional Development

  1. Understand your child’s behavior – particularly if they aren’t verbal – is their way of communicating. Narrate what your child is experiencing and label emotions. For example, “I see you’re angry. Can I help you put your shoes on?”
     
  2. Model social and emotional self-control. For example, “I’m frustrated. I’m going to pause, take deep breaths then tell you what I need.” This gives children coping techniques they can practice themselves.
     
  3. Be a good example. Model, for instance, how to be a good friend, show respect and use good manners.
     
  4. Partner with your child’s teachers. There should be two-way dialogue presenting potential concerns.
     
  5. Don’t rush to diagnose issues. Remember children save their “toxic waste” – big, negative feelings – for their parents because they trust them. Your experiences with your child may be different than others’ experiences. Be cautious to avoid a quick reaction. Work to understand what your child is trying to convey. Seek information from others.
     
  6. If a child is exhibiting anxious behavior, which is normal when encountering new situations, be present, listen, observe, answer questions, label emotions and provide reassurance. Don’t overreact to fears. Young children are learning to deal with the unknown and, just like learning to ride a bike, it takes time and comfort to develop the skills to manage those emotions.

To watch a webinar featuring Loquasto and Pruett providing additional guidance, and access actionable parenting insights and resources, visit the Parent Resource Center at GoddardSchool.com.

Photos courtesy of Shutterstock


SOURCE:
The Goddard School

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