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HEALTHY LIVING

How to talk to your doctor about statin intolerance

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(Family Features) If your doctor has concerns about your cholesterol levels, you may be familiar with statins. This is a class of medications that can help reduce your body’s cholesterol production, lowering your risk of heart attack or stroke.

However, up to 30% of adults in the United States have some degree of statin intolerance, according to research published in the “Journal of Clinical Lipidology.” Possible signs or symptoms of statin intolerance are muscle aches and cramps, fatigue, weakness, elevated liver enzymes and the onset of diabetes or impaired glucose tolerance.

As a result, nearly one-third of patients (29%) discontinue their statin within the first year, according to findings published in the “American Journal of Cardiology.” Unfortunately, patients with statin intolerance are at an increased risk of cardiovascular disease, including higher rates of coronary heart disease and recurrent heart attack.

Lowering Bad Cholesterol
A diagnosis of high cholesterol involves measuring low-density lipoprotein (LDL) cholesterol, which is commonly referred to as “bad” cholesterol because it leads to the accumulation of plaque in your arteries. Plaque reduces your blood flow, which can cause damage to your cardiovascular system.

Bloodwork is the best indicator of your cholesterol levels, since you may not experience any symptoms of high cholesterol until you already have damage and buildup in your arteries.

To help create your treatment plan, talk to your doctor about your medical history, including whether you’ve had a heart attack or any heart procedures, such as a stent placement or bypass surgery. You’ll also review current medications, recent lab results and notes on any symptoms you may be experiencing.

Your doctor is likely to recommend a series of steps to reduce your cholesterol. Some common recommendations include a healthy diet low in saturated and trans fats and high in fiber, especially fruits, vegetables and whole grains.

If you’re not already getting regular physical activity, your doctor will likely encourage you to get at least 30 minutes of exercise daily, find ways to include more movement in your everyday lifestyle and, if necessary, work toward shedding extra weight.

Lifestyle changes can help but may not make a big enough impact to reduce cholesterol to a recommended level. In those cases, doctors rely on cholesterol-lowering medications such as statins. Statins can be highly effective at reducing bad cholesterol, making them a powerful tool to reduce the risks associated with heart disease.

When Statins Are Intolerable or Aren’t Enough
For a variety of reasons, including intolerance to the medication, other health conditions or interactions with other medications, statins may not be the right choice for everyone.

“While statins remain the gold standard for cholesterol lowering, I often see patients who either can’t or won’t take a statin, as well as patients who require further LDL cholesterol reduction,” said Guy L. Mintz, Director of Cardiovascular Health & Lipidolology at Northwell Health System. “For those patients, I prescribe non-statin medications, such as NEXLETOL (an oral prescription medication with the cholesterol lowering agent bempedoic acid) and NEXLIZET (a combination of cholesterol-lowering medicines bempedoic acid and ezetimibe). I am comfortable using NEXLETOL and NEXLIZET, along with a healthy diet and exercise, to reduce LDL cholesterol in adults with high blood cholesterol levels and to reduce risk of heart events. Non-statins are another important therapeutic tool in our lipid lowering toolbox.”

To learn more visit Nexlizet.com.

Photo courtesy of Shutterstock

IMPORTANT SAFETY INFORMATION
What are NEXLIZET tablets and NEXLETOL tablets?

  • Along with a diet:
    • NEXLETOL is used, with other cholesterol-lowering medicines, or alone when use with other cholesterol-lowering medicines is not possible, to reduce low-density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high blood cholesterol called heterozygous familial hypercholesterolemia (HeFH).
    • NEXLIZET is used, with or without other cholesterol-lowering medicines, to reduce low- density lipoprotein (LDL, or bad cholesterol) in adults with high blood cholesterol levels called primary hyperlipidemia, including a type of high cholesterol called heterozygous familial hypercholesterolemia (HeFH).
  • The bempedoic acid portion of NEXLIZET and NEXLETOL is used to lower the risk of heart attack and heart procedures like stent placement or bypass surgery, in adults who are unable to take recommended statin treatment (a cholesterol-lowering medicine), or are not taking a statin, who:
    • have known heart disease, or
    • are at high risk for heart disease but without known heart disease.

Do not take NEXLIZET if you are allergic to ezetimibe or bempedoic acid, or any ingredients in NEXLIZET or NEXLETOL. If you have any of the following signs and symptoms of a serious allergic reaction, call your healthcare provider or go to the nearest hospital emergency room:

  • swelling of your face, lips, mouth, or tongue
  • wheezing
  • severe itching
  • fast heartbeat or pounding in your chest
  • trouble breathing
  • skin rashes, redness, or swelling
  • dizziness or fainting

What should I tell my healthcare provider before taking NEXLIZET or NEXLETOL? Tell your healthcare provider if you:

  • have, or had, gout
  • have or had tendon problems
  • are pregnant or breastfeeding or may become pregnant or plan to breastfeed. It is not known if NEXLIZET or NEXLETOL passes into your breastmilk
  • have severe kidney or severe liver problems

Tell your healthcare provider about all the medicines you take, including prescription and over-the- counter medicines, vitamins and herbal supplements.
Especially tell your healthcare provider if you take or plan to take simvastatin or pravastatin, as taking either with bempedoic acid may increase your risk of developing muscle pain or weakness. If you take NEXLIZET, tell your doctor if you take cyclosporine, fibrates, or cholestyramine.

What is the most important safety information I should know about NEXLIZET and NEXLETOL? NEXLIZET and NEXLETOL can cause serious side effects, including:

  • increased levels of uric acid in the blood, which can lead to gout, a painful joint condition. Call your doctor if you have any of the following symptoms: severe foot pain especially in the toe joint, warm joints, swelling, tender joints or joint redness.
  • tendon rupture or injury. Tendon problems can happen in people who take bempedoic acid, one of the medicines in NEXLIZET or NEXLETOL. The risk of getting tendon problems while you take NEXLIZET or NEXLETOL is higher if you: are over 60 years of age, are taking steroids, are taking antibiotics called fluoroquinolones, have renal failure, or have had tendon problems in the past. Stop taking NEXLIZET or NEXLETOL immediately and get medical help if you experience signs of tendon rupture such as snap or pop in tendon area, bruising after an injury in a tendon area, or unable to move or put weight on the affected area.

The most common side effects in people with primary hyperlipidemia:

  • NEXLETOL includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia and increased liver enzymes.
  • NEXLIZET includes symptoms of the common cold or flu-like symptoms, muscle spasms, back pain, stomach pain, bronchitis, pain in shoulder, legs, or arms, anemia, increased liver enzymes, diarrhea, joint pain, swelling of sinuses and fatigue.

The most common side effects of bempedoic acid, a component of NEXLIZET and NEXLETOL, in people with heart problems include kidney problems, anemia, increased liver enzymes, muscle spasms, and gallstones.

These are not all the possible side effects of NEXLIZET and NEXLETOL. For more information, ask your healthcare provider or pharmacist for more information.

Call your healthcare provider for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


SOURCE:

Esperion

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HEALTHY LIVING

Babyproofing tips for baby safety month

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(Feature Impact) Outsmarting a baby can be harder than it sounds – especially when it comes to transforming your home into a safe place for them to explore. Through their eyes, a coffee table becomes a climbing opportunity, a dangling phone charger looks like a teething toy and a cabinet of cleaning supplies could be an exciting travel destination.

Babyproofing is about anticipating those discoveries before little ones make them. In honor of National Baby Safety Month, consider these tips to make your home safer all year round.

Install Gates and Doorknob Covers

Crawling babies and stairs are a bad combination. Make sure the two never have the chance to meet by securely installing safety gates at the top and bottom of staircases to thwart young explorers. Gates or doorknob covers can also block access to other rooms and areas you’d prefer to keep off limits, like kitchens, bathrooms and laundry areas.

Use Safety Latches Wisely

Cabinets and drawers can contain a myriad of dangerous items, from cleaning products to sharp objects and medications. Even if you have rooms gated off, treat safety latches and locked storage receptacles as a second line of defense to make sure babies and toddlers can’t rummage where they shouldn’t.

Stress-Test Furniture

As babies and toddlers transition from crawling to walking, they often try using furniture to pull themselves up. Tall or unstable objects like TV stands, small tables and bookshelves can tip over if they aren’t properly secured. Try giving these objects a shake to see whether they’re easily moveable or wobbly; if so, anchor them to the floor or wall when possible. While you’re at it, check for sharp corners at the right height to bonk little heads and cover them with softer edge protectors.

Cover Outlets and Stow Cords

Electrical outlets can be tempting targets for curious fingers. Outfit them with covers or plastic safety caps, especially if you don’t already have tamper-resistant receptacles with built-in mechanisms to block foreign objects from entering the slots. As you’re going about your outlet audit, pay attention to cords as well. When possible, tuck them away or secure them with cord organizing systems, and block access to objects like lamps where cords can be used for tugging and toppling.

See the World at Their Level

Although it might feel silly, one of the best ways to spot hazards around your home is to scout for them from a baby’s perspective. Try getting as close to the floor as you can then look around each room for anything that could interest a young child and pose potential danger. In particular, keep an eye out for small objects that could become choking hazards, like dropped coins, batteries or loose toy pieces.

As children grow, so do the needs of your space. Visit eLivingtoday.com for more ideas on designing your home to fit your family.

Photo courtesy of Unsplash

    

SOURCE:

eLivingtoday.com

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HEALTHY LIVING

Daily brain health habits for better cognition

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(Feature Impact) Your brain works hard for you, so it’s only fair to return the favor by practicing simple everyday habits to keep this important organ strong and thriving.

Start by tweaking your daily routine to focus on these four habits.

Prioritize Sleep

Getting quality sleep is vital for proper brain function. If you find you’ve slipped into the habit of staying up later than you should or notice your sleep being disrupted during the night, those are signs to revisit your sleep hygiene practices. Start by establishing a regular bedtime and wake-up time that will give you the recommended 7-9 hours of sleep. Turn your bedroom into a comfortable refuge from the world – keep it cool and dark, and set up fans or noise machines if you need them to quiet your mind. Avoid consuming caffeine or alcohol too close to bedtime and try switching to a book instead of a screen when it’s time to wind down.

Eat Smart

Just like the rest of the body, the brain is nourished by food. Some of its favorite foods are options rich in healthy fats like fish, avocado, olive oil and nuts, as well as vegetables like leafy greens, which offer carotenoids, and fruits such as grapes, which deliver antioxidants and other polyphenols.

Combine several of these powerful brain-boosting foods at once with this California Grape and Sardine Avocado Toast recipe. The fish is rich in omega-3 fatty acids and the avocado offers a boost of healthy unsaturated fat, while the grapes add protective dietary flavonols, which may help promote anti-inflammatory and beneficial antioxidant activity.

A study published in the scientific journal “Neurology” found a higher intake of certain flavonols – including three naturally found in grapes – is associated with a 48% decreased risk of developing Alzheimer dementia.

Get Moving

Adding even more proof that what’s good for your body is good for your mind, getting regular exercise is one of the best things you can do for your brain. Motivate yourself by choosing a form of movement you genuinely enjoy, whether it’s a daily walk on a nearby nature trail, a dance class, a bike ride or a heart-pumping workout video.

Challenge Your Mind

Don’t forget to give your brain its own workout, too. Doing something mentally stimulating every day is a great way to keep yourself sharp, and there are plenty of ideas to choose from. Try learning a new language, picking up a musical instrument, playing a mind-engaging card or board game, doing a puzzle, reading a book or immersing yourself in a creative writing or art project. The options are nearly endless, and if you want to make your brain extra happy, you can snack on handfuls of grapes as you enjoy your hobby.

Learn more about the connection between grapes and brain health and discover more recipes by visiting GrapesFromCalifornia.com.

California Grape and Sardine Avocado Toast

Prep time: 10 minutes
Servings: 4

  • 1          large firm, ripe avocado, halved and pitted
  • 4          small slices rustic whole grain bread (1/2-inch thick), toasted or grilled
  • 1          individual container sardines in olive oil or water, drained
  • 1/2       cup quartered red and black Grapes from California
  • Aleppo pepper flakes
  • fresh cilantro, snipped
  • 1          lemon half
  • salt (optional)
  1. With spoon, scoop avocado out of skin and use fork to coarsely mash.
  2. Spread onto bread slices and top with whole or torn sardines. Sprinkle grapes over sardines.
  3. Top with generous sprinkle of Aleppo pepper, cilantro, squeeze of fresh lemon and salt, if desired.

Nutritional information per serving: 290 calories; 11 g protein; 29 g carbohydrates; 16 g fat (50% calories from fat); 2.5 g saturated fat (8% calories from saturated fat); 20 mg cholesterol; 210 mg sodium; 6g fiber.

    

SOURCE:

California Table Grape Commission 

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HEALTHY LIVING

Protein-packed snacking for school season

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Protein-Packed Snacking for Back-to-School Season

(Feature Impact) As busy families prepare for hectic school days, it can be invaluable to have nutritious grab-and-go options on hand for lunches and snacks. Having one less thing to worry about makes a difference when you’re juggling work, school, sports practices and games, and other extracurriculars while trying to keep everyone fed and happy.

Watch this video to learn more

https://youtube.com/watch?v=rcOWxH84piA%3Fsi%3D_oG-Zy0gb690Z4YE%26controls%3D0

Since protein is an important nutrient for energy and satiety, choosing options like PB2Go Cups could be the perfect solution. As the pioneer of powdered peanut butter, PB2 has made it more portable than ever with the introduction of their new, on-the-go cups.

With 10-11 grams of protein per cup, they’re easy to toss in a lunchbox or backpack, offering a convenient way to keep your family powered up through the afternoon. Simply add water to the fill line, stir with the built-in spoon and enjoy the Original or Chocolate Chip flavors on their own or as a dip with pretzels, crackers, apple slices or bananas for more flavor and fun during your snack break.

“Between packed lunches, busy schedules, and after-school activities, convenient protein options are a game changer,” said registered dietitian Mia Syn, a food and nutrition expert. “That’s why I love PB2Go Cups. With a built-in spoon in the lid, they’re ready to toss in a lunch box, backpack, or gym bag and enjoy wherever the day takes you.”

Whether you’re tackling early-morning school prep or searching for a ready-when-you-are snack to keep in your locker, powdered peanut butter is a healthy, satisfying choice. No stress and no mess makes for a winning combination, and families who value balanced nutrition will appreciate having a quick, pre-portioned source of protein on hand when their schedules are full.

For more information, visit PB2.com.

   

SOURCE:

PB2Go

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